PEOPLE
Cassie Spracklen
B.A. | M.S. | Ph.D.
Dr. Spracklen received her B.A. in Biology from Anderson University in 2009. She received both her M.S. and PhD in Epidemiology from the University of Iowa in 2011 and 2014, respectively. During her PhD, Dr. Spracklen’s research centered around reproductive and perinatal epidemiology with a focus on adverse pregnancy outcomes and lifecourse epidemiology. Dr. Spracklen’s dissertation, guided by Drs. Audrey Saftlas and Kelli Ryckman, was entitled “Dyslipidemia and the risk of preeclampsia: genetic causes and related modifiers”, and capitalized on data available from an NIH-funded case-control study called the Study of Pregnancy-induced Hypertension in Iowa (SOPHIA).
After completing her dissertation, Dr. Spracklen completed a five-year postdoctoral research fellowship in Genetic Epidemiology at the University of North Carolina-Chapel Hill with Dr. Karen Mohlke. At UNC, her research interests focused around understanding the genetic architecture of complex cardio-metabolic traits (e.g. lipids, adiponectin, T2D), particularly among non-European ancestry populations. Her work was conducted in both single cohort studies (MESTIM, CHNS, CLHNS) and very large meta-analyses as a part of international consortia efforts.
Dr. Spracklen joined the Department of Biostatistics and Epidemiology in the School of Public Health and Health Sciences at the University of Massachusetts Amherst as an Assistant Professor in 2019. As of September 2024, she has been promoted to Associate Professor with tenure!
Outside the office, you will find Dr. Spracklen walking or jogging (slowly!) on the Norwich Trail or hiking in one of the nearby state parks with her husband and young daughter. You can also find her buying fabric for her next quilt project, touring wineries, or traveling around the world!
- EMAIL: cspracklen[at]umass.edu
- Download Current CV
Current Group Members
Christian Daniele
PhD Epidemiology Student (2024-)
PhD Dissertation: TBD
- EMAIL: cdaniele[at]umass.edu
Goodness Biney
PhD Epidemiology Student (2024-)
PhD Dissertation: TBD
MS Thesis (2023-2024): Age at T2D diagnosis, depression, and risk of cardiovascular outcomes
- EMAIL: gbiney[at]umass.edu
Rachel Wacks
PhD Epidemiology Student (2023-)
PhD Dissertation: Biological and Modifiable Risk Factors for Adverse Pregnancy Outcomes in the Iowa Health in Pregnancy Study
- EMAIL: rwacks[at]umass.edu
Chi Zhao
PhD Epidemiology Student (2021-)
Research Projects: Trans-ethnic meta-analysis and fine-mapping analyses (GIANT consortium); identifying mechanisms influencing T2D risk (collaboration with Stitzel/Ucar groups at JAX); lipid GWAS and fine-mapping in the CHNS
PhD Dissertation: Investigating the Genetic Architecture of Type 2 Diabetes and Complications
- EMAIL: czhao[at]umass.edu
Former Group Members
Goodness Biney
MS in Epidemiology Student (2023-2024)
MS Thesis: Age at T2D diagnosis, depression, and risk of cardiovascular outcomes
Manuscript in preparation
- EMAIL: gbiney[at]umass.edu
Christian Daniele
4+1 MS in Epidemiology Student (2021-2023)
Research Project: Associations between a women’s birth weight and gestational age and her longterm reproductive health and pregnancy outcomes
Thesis Project: Associations between a women’s birth weight and gestational age and the risk of hypertension
Manuscript in preparation
- EMAIL: cdaniele[at]umass.edu
Caitlin Fields
MPH in Epidemiology Student (2021-2022)
MPH Project: The effect of the microbiome on rheumatoid arthritis risk: literature review and steps for the future
Spencer Friedman
Undergraduate informatics, Biochemistry Student (2022-)
- EMAIL: spencerfried[at]umass.edu
Isabella “Izzy” Gleckman
4+1 MPH in Epidemiology Student (2019-2020)
MPH Project: Patterns of smoking cessation and risk of low birth weight
Lichen Hao
PhD Epidemiology Student (2021-2023)
- EMAIL: lhao[at]umass.edu
Aaron Holman-Vittone
MS in Epidemiology Student (2021-2022)
MS Thesis: Preterm birth and subsequent risk of type 2 diabetes among postmenopausal women in the Women’s Health Initiative
Savannah Kangas
MPH in Epidemiology Student (2021-2022)
MPH Project: Incidence of congenital heart defects in offspring born to women with type 2 diabetes
Brian Monahan
MS IN EPIDEMIOLOGY STUDENT (2020-2021)
MS Thesis: Birthweight and Subsequent Risk of Autoimmune and Thyroid Conditions in the Women’s Health Initiative (WHI)
Emily Nyhan
MS Epidemiology Student (2023-2024)
MS Thesis: Maternal birthweight and preterm birth and risk for Alzheimer’s Disease
Manuscript in preparation.
- EMAIL: enyhan[at]umass.edu
Nora Salo
4+1 MPH IN EPIDEMIOLOGY STUDENT (2020-2021)
MPH Project: Racial and Ethnic Disparities in the Association Between Maternal Depression during Pregnancy and Preterm Birth Risk among Women in the United States
Vishal Kumar Sarsani
PhD in Statistics Student (2021-2023)
Research Project: Trans-ethnic meta-analysis of genome-wide association studies of adiponectin and the effect of adiponectin on cardiometabolic traits
- EMAIL: vsarsani[at]umass.edu
Christina Ziogas
Undergraduate Public Health STUDENT (2019-2021)
Project: Validation of Maternal Recall and Birth Certificate Data of Events in Labor and Delivery with Medical Records in the Iowa Health in Pregnancy Study (IHIPS)