Adverse pregnancy and birth outcomes are a critical public health issue. Globally, over 30% of all pregnancies and/or births are affected by at least one adverse outcome including preterm birth, low birth weight, small- or large-for-gestational age, preeclampsia, gestational hypertension, and gestational diabetes. Any one of these outcomes can result in immediate or long-term morbidities or mortality for both mom and baby.
We are interested in identifying genetic and non-genetic risk factors that result in one of these (or other) adverse outcomes, striving to find methods for prevention. Our research has the potential to greatly improve public health around the globe, preventing both maternal and infant morbidities and mortality.
Iowa Health in Pregnancy Study (IHIPS)
IHIPS is a population-based case-control study designed to determine the influence intimate partner violence, maternal stress, and other maternal and paternal factors on the risks of preterm and small-for-gestational age births. Participants were selected among live-births to residents of four Iowa counties. Study data comes from medical record data, birth certificates, and self-report during a detailed telephone interview.
Study of Pregnancy-induced Hypertension in Iowa (SOPHIA)
SOPHIA is a population-based case-control study of preeclampsia and gestational hypertension specifically designed to examine the hypothesis that increased cumulative exposure to paternal seminal fluid would decrease the risk of preeclampsia. Participants were selected among live-births to residents throughout the state of Iowa. Study data comes from medical record data, birth certificates, and self-report during a detailed telephone interview.